Playing without Joel Embiid, Tyrese Maxey, VJ Edgecombe and Paul George, the Sixers fell to James Harden and the Cleveland Cavaliers 115-101 on Monday night, dropping to 34-30 on the season as they try to navigate this injury plagued portion of the season. The Sixers lost the season series to the Cavs 4-0.

Quentin Grimes led the Sixers with 17 points, 5 rebounds and 3 assists in a throwback performance straight out of March 2025. Cam Payne added 12 points and 4 assists, and Justin Edwards added 14 off the bench in a losing effort.

James Harden led the Cavs with 21 points and 5 assists, with Keon Ellis adding in 19 off the bench.